Advanced Nutrients by Thorne Details and Interactions (2025)

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• Ascorbic Acid

Vitamin D is a fat-soluble vitamin that plays a crucial role in several bodily processes. It helps the body absorb calcium and phosphorus, which are necessary for healthy bones and teeth. It is also important for immune system function and may help to protect against certain diseases.Vitamin D is found in a variety of foods, including fatty fish, egg yolks, and fortified foods such as milk and cereal. It is also produced by the body when the skin is exposed to sunlight.Vitamin D supplements are available in a variety of forms, including tablets, capsules, and liquids. The recommended daily intake of vitamin D varies depending on age, sex, and other factors, and it is important to follow the dosage recommendations provided by a healthcare professional. There are several different forms of vitamin D available, with the two most popular being ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3).

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• Vitamin D3

Vitamin E is a fat-soluble vitamin found naturally in a variety of foods, including vegetable oils, nuts, seeds, and leafy green vegetables. Vitamin E is also available as a dietary supplement and is often added to skincare products.Vitamin E has many roles in the body, including protecting cells from oxidative stress and supporting immune function.

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• Thiamine Hydrochloride

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• Riboflavin 5'-Phosphate Sodium

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• Pyridoxal 5-Phosphate

Vitamin B12, also known as cobalamin, is a water-soluble vitamin crucial for several bodily functions. It plays a pivotal role in the formation of red blood cells, aiding in the prevention of anemia. Vitamin B12 is essential for maintaining a healthy nervous system and proper brain function, as it is involved in the synthesis of myelin, the protective sheath around nerve fibers. This vitamin is primarily found in animal-based foods such as meat, fish, dairy products, and eggs, making it important for vegetarians and vegans to consider supplementation. A deficiency in vitamin B12 can lead to neurological issues, fatigue, and cognitive impairment.

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• Methylcobalamin

Biotin, also known as vitamin H or vitamin B7, is a water-soluble vitamin that plays a role in various metabolic processes in the body. It is necessary for the growth and maintenance of healthy skin, hair, and nails, and is also involved in the metabolism of carbohydrates, fats, and amino acids. Biotin is considered to be generally safe when consumed in the recommended daily amounts but it is important to note that consuming large amounts of biotin-containing supplements or products can cause falsely high or falsely low test results for certain laboratory tests, such as those for thyroid function, hormone levels, and certain biomarkers for certain diseases.

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• Calcium Pantothenate

Choline is an essential nutrient that is found in many foods, including eggs, and is important for a number of bodily functions, including liver function, brain development, and nerve function.Choline is a precursor to acetylcholine, a neurotransmitter that plays a role in memory, mood, and muscle control. Choline also helps to transport fats out of the liver, which may help to reduce the risk of liver disease.Choline supplements are available in different forms, including choline bitartrate, choline chloride, and phosphatidylcholine. Choline bitartrate is the most common form of choline supplement, but phosphatidylcholine is the form that is found naturally in foods.

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• Choline Citrate

Calcium is a vital nutrient found in various foods such as dairy products, certain vegetables, and many fortified items. Over 99% of the body's calcium is stored in the bones and teeth, predominantly as hydroxyapatite. The remaining calcium circulates in the blood, extracellular fluid, muscles, and other tissues, where it is essential for processes like nerve signaling, muscle contraction, vascular activities, glandular secretion, and maintaining cell membrane and capillary permeability. It also plays critical roles in enzyme reactions, respiration, kidney function, and blood clotting, and is involved in neurotransmitter and hormone release, amino acid uptake, vitamin B12 absorption, and gastrin secretion.Calcium balance changes with age: it is positive during periods of growth, stable in adulthood, and tends to become negative in older age. Calcium loss occurs through feces, urine, sweat, and shedding skin cells. In women, reduced estrogen levels decrease calcium absorption and retention, increase bone turnover, and lead to lower bone mass.Calcium supplements come in various forms, including citrate and carbonate, which differ mainly in their calcium content and absorption rates. Calcium citrate is easily absorbed and can be taken without food, making it suitable for older adults or those with low stomach acid. In contrast, calcium carbonate, which contains a higher percentage of calcium, is best absorbed when taken with meals.

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• DimaCal Dicalcium Malate

Iodine is a mineral that is crucial for our body's ability to produce thyroid hormone, which helps control our growth, metabolism, and energy levels. A lack of iodine in the diet is a common problem around the world and can lead to intellectual development issues. Adding iodine to salt (i.e., iodized salt) has helped reduce this problem. Iodine is commonly utilized as a dietary supplement, both in multivitamin preparations and as a standalone ingredient as it is purported to have overall health and wellness benefits, not just in those who are deficient. One such standalone iodine product is 'Iodoral'. Studies have shown iodine supplementation may help improve cognitive function and boost energy levels but more research is needed. It is recommended that you should be under medical supervision if you plan on taking iodine as there may be a risk of certain side effects with high dosages.

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• Potassium Iodide

Magnesium is a mineral that is essential for the proper functioning of the body. It plays a role in many important physiological processes, including the contraction and relaxation of muscles, the transmission of nerve impulses, and the regulation of blood pressure. Magnesium is found in a variety of foods, including leafy green vegetables, nuts, and grains, and it is also available as a dietary supplement.There are several different forms of magnesium that are available as supplements, all of which can be used to prevent deficiency. Additionally, magnesium is purported to have several different health benefits, such as improving sleep, reducing muscle cramps, reducing anxiety, and preventing or treating migraines.Although magnesium is essential for health, magnesium-containing foods and supplements can interact with some prescription medications if used at the same time.

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• DiMagnesium Malate

Zinc is a mineral that is essential for the proper functioning of the human body. It is involved in many important physiological processes, including immune system function, wound healing, taste, and smell. Zinc is found in a variety of foods, including meat, seafood, and whole grains, and it is also available as a dietary supplement.Zinc supplements may be used to treat or prevent zinc deficiency, which can occur due to certain medical conditions, such as gastrointestinal disorders, alcohol abuse, and certain medications. Zinc supplements may also be used for other purposes, such as to boost the immune system, improve acne, and reduce the severity and duration of colds.There are several different forms of zinc supplements available, including zinc gluconate, zinc acetate, and zinc sulfate. The most common form of zinc supplements is zinc gluconate, which is well absorbed and is less likely to cause stomach-related side effects than other forms of zinc.

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• TRAACS Zinc Bisglycinate Chelate

Selenium is an essential trace element that plays a crucial role in various physiological functions in the human body. It is often included in dietary supplements due to its antioxidant properties and its contribution to maintaining a healthy immune system. Selenium is important for thyroid function and may also have a role in protecting against certain chronic diseases. However, it's essential to note that excessive selenium intake can be harmful, so it's crucial to adhere to recommended daily allowances and consult with a healthcare professional before taking selenium supplements.

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• L-Selenomethionine

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• Copper Bisglycinate Chelate

Manganese is an essential trace mineral that plays a vital role in various physiological processes within the human body. It is required for proper brain function, bone formation, enzyme activation, and wound healing. Manganese also contributes to metabolism, antioxidant defense, and the formation of connective tissues.

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• TRAACS Manganese Bisglycinate Chelate

Chromium is a trace mineral that is found in small amounts in the human body. It is believed to play a role in the metabolism of carbohydrates, fats, and proteins. It is used as a dietary supplement for its purported ability to help with weight loss and blood sugar control.There is some evidence to suggest that chromium supplements may help to improve blood sugar control in people with type 2 diabetes, although the results of studies on this topic have been mixed. Some studies have found that chromium supplements can improve insulin sensitivity and reduce blood sugar levels in those with poorly controlled diabetes, while others have found no significant effects.

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• TRAACS Chromium Nicotinate Glycinate Chelate

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• Phospholipid
• Sophora japonica extract

Bilberry is a small, perennial shrub that belongs to the Ericaceae family and is native to Europe, the northern United States, and Canada. It is known for its small, dark purple berries, which are similar in appearance to blueberries. The name bilberry is derived from the Danish word 'bollebar', meaning "dark berry". Bilberry is high in antioxidants, including flavonoids, and are a good source of vitamins and minerals, including vitamin C, vitamin E, and manganese. Bilberry has a long history of use in traditional medicine and is claimed to have a number of potential health benefits, including improving vision, reducing inflammation, and treating diarrhea.

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Resveratrol is a natural compound found in certain plants, including grapes, berries, and peanuts. It has been the subject of numerous scientific studies due to its potential health benefits. Some research suggests that resveratrol may have antioxidant, anti-inflammatory, and cardioprotective effects. It may also have potential as a cancer-fighting agent and may help to improve glucose metabolism and insulin sensitivity.

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Boron is a trace mineral that is found in a variety of foods, including fruits, vegetables, nuts, and legumes. It is also available as a dietary supplement. Boron is thought to play a role in bone health, as it may help the body metabolize calcium, magnesium, and phosphorus. Some preliminary research also suggests that boron may have anti-inflammatory effects and may help to improve cognitive function. However, more research is needed to confirm these potential benefits.It is important to note that boron is not an essential nutrient and deficiency is rare. The recommended dietary allowance (RDA) for boron is not established, however, the safe upper limit is 20mg/day. Taking high doses of boron can cause skin irritation, nausea, vomiting, and diarrhea. There are several patented forms of boron available in dietary supplements, such as Albion Bororganic Glycine.

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• Bororganic Boron Glycinate Complex